Abstracts: Yamane K (1989)
Yamane K, Hashimoto S, Kobayashi I, Maruyama S (1989) [Basilar artery migraine
associated with transient global amnesia]. [Japanese. No To Shinkei 41:1103-1107
Transient global amnesia (TGA) is an unusual form of the amnestic syndrome, clinically
characterized by profound disturbance of short-term memory with preservation of immediate
recall and long-term memory. Spontaneous recovery is the rule and is usually complete
within several hours. The etiology of TGA is not clear. It is considered to be caused by
transient ischemia confined to the medial temporal lobe, an area supplied by branches of
the vertebrobasilar system. Basilar artery migraine is a well-known syndrome, first
described by Bickerstaff. Besides pulsating headache, the dominant symptoms are vertigo,
ataxic gait, tinnitus, dysarthria, paraeshesia in the hands, homonymous hemianopsia and
sometimes drop-attacks. These symptoms are associated with vertebrobasilar system
dysfunction. In this paper, three migraine patients, suffering from one episode of TGA,
were reported. All patients were women. Case 1 was a 48-year-old woman with a history of
common migraine. Case 2 was a 48-year-old woman with a history of classic migraine. Case 3
was a 59-year-old woman with a common migraine. Family history of migraine exists in case
1 and case 3. Their migrainous attacks began in their twenties and thirties. They suddenly
suffered migraine with the symptoms of vertebrobasilar dysfunction. These symptoms are
ataxic gait (Case 1, 2, 3), dysarthria (Case 1, 2), vertigo (Case 1, 3) and homonymous
hemianopsia (Case 1, 3). Simultaneously three patients had TGA. Duration of retrograde
amnesia were about twenty-four hours (Case 1), about thirty minutes (Case 2) and about
three hours (Case 3).
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